Lung caner
Conditions
Interventions
Experimental group:On the basis of the control group, the experimental group was given a traditional Chinese medicine formula based on Shamaidong Tang at the same time, orally for two weeks, stopped f
Control group:Pemetrexed was treated in combination with cisplatin, bevacizumab, and sintilimab
Sponsors
Jinshazhou Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Pathologically diagnosed as lung adenocarcinoma with distant metastasis; 2. EGFR wild-type, ALK negative; 3. TCM diagnosis: deficiency of both qi and yin: fatigue, weakness, dry mouth and little thirst, red or pale tongue, weak pulse; 4. Age 18-80 years old (including 18 years old and 80 years old), gender not limited; 5. Expected survival period exceeds three months; 6. No previous use of pemetrexed combined with cisplatin chemotherapy, and currently suitable for this chemotherapy regimen; 7. ECOG score <= 2 points; 8. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. There is brain metastasis; 2. Severe liver and kidney function impairment (liver function at Child-C stage, kidney disease at stage 4-5); 3. Other immunotherapies have been applied; 4. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| INF-?;T lymphocyte subpopulation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions;PFS(Progression Free Survival); | — |
Countries
China
Contacts
Public ContactXiang Li
Jinshazhou Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed