Progressive Pulmonary Fibrosis
Conditions
Interventions
Observation Group:None
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years, regardless of gender; 2. Have a diagnosis of PPF after March 1, 2023 (with a combination of high-resolution CT (HRCT), pulmonary function test, etc.) and at least 1 follow-up visit within 1 year of diagnosis; 3. Have a clear medical record and diagnosis based on at least one chest CT within 6-12 months of diagnosis, and based on the last CT in a 1-year period; 4. Received at least 1 antifibrotic therapy.
Exclusion criteria
Exclusion criteria: 1. Patients enrolled in another unblinded interventional lung disease-related study prior to enrollment; 2. Patients with serious comorbidities or other conditions (e.g., unrecovered major surgery or trauma, etc.) that, in the judgment of the investigator, may affect the conduct of the study or interpretation of the results; 3. Serious heart disease, such as New York Heart Association (NYHA) Class II-IV heart failure, unstable angina, myocardial infarction, or severe arrhythmia; 4. Uncontrolled hypertension (systolic blood pressure > 160 mmHg and/or diastolic blood pressure > 100 mmHg); 5. Active infections such as human immunodeficiency virus (HIV) infection, active tuberculosis or other infectious diseases requiring systemic anti-infective therapy; 6. Severe liver disease or kidney disease, such as cirrhosis, liver failure, severe hepatitis, chronic kidney disease requiring dialysis, or acute renal failure; 7. Other conditions deemed inappropriate for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary Function Indicators(FVC?FVC%?FEV1,etc); | — |
Secondary
| Measure | Time frame |
|---|---|
| Diffusing Capacity of the Lungs for Carbon Monoxide (DLCO); | — |
Countries
China
Contacts
Public ContactBai Jiuwu
Shanghai Pulmonary Hospital
Outcome results
None listed