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Analysis of Dose and Dose-averaged Linear Energy Transfer Synergistic Effects on Rib Fractures in Breast Cancer Proton Therapy

Analysis of Dose and Dose-averaged Linear Energy Transfer Synergistic Effects on Rib Fractures in Breast Cancer Proton Therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128787
Enrollment
Unknown
Registered
2026-07-26
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Proton therapy rib fracture cohort:None

Sponsors

The Clinical Technology Research And Development Center of Shanghai Proton and Heavy Ion Center
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Pathologically confirmed breast cancer; 2. Received PBS proton therapy; 3. Follow-up imaging (CT/MRI/PET-CT) clearly diagnosed as radiation-induced rib fracture; 4. Have complete original planning CT and treatment plan;

Exclusion criteria

Exclusion criteria: 1. History of r ation therapy on the same side of the chest; 2. Bone metastasis or other definite non-radiation-related bone lesions.

Design outcomes

Primary

MeasureTime frame
Radiation-induced rib fracture status;—

Secondary

MeasureTime frame
Model predictive performance metrics;—

Countries

China

Contacts

Public ContactJingfang Zhao

The Clinical Technology Research And Development Center of Shanghai Proton and Heavy Ion Center

jingfang.zhao@sphic.org.cn+86 21 38296666

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026