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Study on Endocrine and Metabolic Abnormalities in Patients with Empty Sella Syndrome

Study on Endocrine and Metabolic Abnormalities in Patients with Empty Sella Syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128771
Enrollment
Unknown
Registered
2026-07-25
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary empty sella syndrome (partial and complete)

Interventions

Pituitary empty sella syndrome patients:None

Sponsors

The first hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients presenting to our hospital between December 2018 and December 2025; 2. Aged > 18 years; 3. Primary empty sella syndrome (ESS, including total empty sella [TES] and partial empty sella [PES]) indicated by pituitary magnetic resonance imaging (MRI).

Exclusion criteria

Exclusion criteria: 1. History of severe hepatic and renal diseases; 2. History of central nervous system (CNS) surgery or radiotherapy; 3. Pituitary or central nervous system neoplasms; 4. Pregnancy or lactation; 5. Use of medications interfering with endocrine function of the pituitary-gonadal, pituitary-adrenal and pituitary-thyroid axes, or prolactin secretion; 6. Missing key clinical data.

Design outcomes

Primary

MeasureTime frame
Cortisol and adrenocorticotropic hormone (ACTH);Pituitary MRI;Prolactin;Thyroid function;Sex hormones;

Secondary

MeasureTime frame
Bone mineral density;Nutritional status parameters;Lipid metabolism parameters;Liver and kidney function parameters;Bone metabolism parameters;Glucose metabolism parameters;Serum electrolyte parameters;

Countries

China

Contacts

Public ContactLiu Yunfeng

The first hospital of Shanxi Medical University

nectarliu@163.com+86 351 4639756

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026