Diseases requiring abdominal surgery, including gastric, intestinal and hepatic tumors, hepatolithiasis, uterine fibroids, uterine and ovarian neoplasms, etc.
Conditions
Interventions
Intrathecal group:Intrathecal hydromorphone group
TAP group:Ultrasound-guided abdominal transversus abdominis plane block with 60ml 0.2% ropivacaine
Sponsors
The First People's Hospital Of Longquanyi District Chengdu
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. age >= 18 years; 2. American Society of Anesthesiologists (ASA) physical status classification I to III; 3. patients undergoing elective abdominal surgery graded III–IV with an operation duration of no less than 2 hours.
Exclusion criteria
Exclusion criteria: 1. BMI =30 kg/m²; 2. Patients with contraindications to neuraxial procedures, including those with coagulation disorders (defined as platelet count 1.5, or current anticoagulant use), spinal deformities, a history of spinal trauma or spinal surgery, severe chronic lumbago, infection at the puncture site, or radiologically confirmed osseous tumor metastasis; 3. Patients with severe comorbidities such as hepatic or renal insufficiency, cardiac or respiratory dysfunction, and those expected to be transferred to the ICU postoperatively; 4. Patients with chronic pain or chronic opioid exposure (opioid use for >=3 months daily, or morphine >=60 mg/d for at least 1 month); 5. Allergy to any study-related medications; 6. Patients with language barriers who cannot understand preoperative education, assessment scales, or the operation procedure of analgesic pumps; 7. Participation in another clinical trial within 3 months prior to enrollment in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative pain intensity during mobilization within the first 24 h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative pain intensity during mobilization within the 48and 72h postoperatively;adverse effect;Postoperative recovery outcomes; | — |
Countries
China
Contacts
Public ContactLiu Hongxin
The First People's Hospital Of Longquanyi District Chengdu
Outcome results
None listed