Liver diseases that fulfill the criteria for partial hepatic resection
Conditions
Interventions
Restricted fluid group:Restrictive fluid therapy
TTE-guided fluid group:Fluid therapy under the TEE-guided
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.The anesthesia classification (ASA classification) is from I to III level; 2.Study participants scheduled to undergo liver resection under general anesthesia;
Exclusion criteria
Exclusion criteria: 1.Second liver surgery; 2.Previous history of upper abdominal surgery; 3.History of acute upper gastrointestinal bleeding recently; 4.liver function classified as Child-Pugh grade C; 5.Esophageal varices grade 3; 6.Renal insufficiency (estimated glomerular filtration rate < 30 mL/min/1.73 m²); 7.Under the age of 18; 8.Pregnancy or lactation period; 9.Do not sign the informed consent form;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The lactic acid level at the end of the surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Central venous pressure (CVP) and blood lactate levels before the start of the operation, at the end of hepatic vein occlusion, during skin suturing, and after extubation;The occurrence of postoperative complications;The data monitored by TEE, such as the left ventricular end-diastolic area, the number of observations of K's sign, EF value, etc;Blood loss, dosage of vasoactive drugs, total fluid infusion volume, urine output, and diuretic usage;Restoration quality score;The time of first getting out of bed after the operation and the time of first exhaust and defecation after the operation, Total length of hospital stay; | — |
Countries
China
Contacts
Public ContactMing Yan
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed