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Analysis of Real-World Effectiveness of Prophylactic Interventions for Postoperative Nausea and Vomiting Based on the Apfel Risk Stratification System

Analysis of Real-World Effectiveness of Prophylactic Interventions for Postoperative Nausea and Vomiting Based on the Apfel Risk Stratification System

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128726
Enrollment
Unknown
Registered
2026-07-24
Start date
2026-07-25
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Interventions

Guideline-compliant group (exposed group):None
Non-compliant group (non-exposed group):None

Sponsors

The Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Aged >= 18 years old; 2.Patients undergoing non-cardiac surgery under general anesthesia; 3.Eligible for Apfel risk stratification assessment (based on four risk factors: female sex, non-smoker, history of PONV or motion sickness, and postoperative opioid analgesia);

Exclusion criteria

Exclusion criteria: 1.Pregnant or breastfeeding women; 2.Patients administered antiemetic drugs within 24 hours before surgery; 3.Patients planned to be transferred to the intensive care unit (ICU) postoperatively;

Design outcomes

Primary

MeasureTime frame
Incidence of PONV within 24 hours postoperatively (defined as any episode of nausea or vomiting);

Secondary

MeasureTime frame
Matching Degree of Apfel Risk Stratification vs Actual Prophylaxis;Surgical Factors (Type, Duration);Types and Doses of Antiemetic Medications;Postoperative Rescue Antiemetic Utilization;

Countries

China

Contacts

Public ContactXiaohua Zou

The Affiliated Hospital of Guizhou Medical University

562931613@qq.com+86 851 86773956

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026