Acute ischemic stroke, carotid artery dissection
Conditions
Interventions
Observation Group:None
Sponsors
The Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 100 years old; 2. Upon initial onset, patients present with mild headache (VAS scale < 4) or mild dizziness (DHI scale <= 10), and no symptoms such as stroke, syncope, amaurosis, transient ischemic attack, severe headache, or dizziness caused by carotid artery dissection. Imaging examination confirms the diagnosis of acute CAD; 3. The patient or their family members sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant or breastfeeding; 2. mRS score >= 2 before onset; 3. Cardiogenic stroke or potential cardiogenic thrombus, with any of the following definite causes of cardiogenic embolism: chronic or paroxysmal atrial fibrillation, mitral stenosis, mechanical valve, endocarditis, intracardiac thrombus or implant, dilated cardiomyopathy, spontaneous echo contrast in the left atrium; 4. Blood glucose 22.2 mmol/L, platelet count 185 mmHg or diastolic blood pressure >110 mmHg, and uncontrollable with antihypertensive medication; 14. Carotid artery dissection caused by iatrogenic or traumatic injury; 15. Contraindications to the use of antiplatelet or anticoagulant agents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical outcomes within 90 days: composite indicators of new ischemic stroke, severe intracranial and extracranial bleeding events, and death; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrent carotid artery dissection (including retinal infarction);Any TIA;Death;Newly diagnosed ischemic stroke;Independence of daily living activities at 3 and 6 months (mRS score 0-2);Good functional outcomes at 3 and 6 months (mRS score 0-1); | — |
Countries
China
Contacts
Public ContactZi Wenjie
The Second Affiliated Hospital of Army Medical University
Outcome results
None listed