Iron Overload
Conditions
Interventions
Low-dose carotenoid supplementation group:Low-dose carotenoid supplementation group (8mg/d)
High-dose carotenoid supplementation group:High-dose carotenoid supplementation group(16mg/d)
Sponsors
Institute of Nutrition and Health, Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The diagnostic criteria for iron overload refer to relevant medical guidelines, e.g., the range of serum ferritin: males (200~500 µg/L), females (150~500 µg/L); 2. No mental illness and normal consciousness; 3. Being informed of this study and signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who have taken other medications (e.g., steroids, antibiotics) within four weeks before enrolling in the study; 2. Those with a history of blood transfusion, blood loss, blood donation, or surgery in the recent six months; 3. Those with iron overload-related diseases or genetic disorders (e.g., hemochromatosis, transfusion-induced iron overload); 4. Pregnant or lactating women; 5. Those with known cardiovascular diseases, diabetes, liver or kidney diseases, malignant tumors, infectious diseases, other familial genetic diseases, autoimmune diseases, or atopic diathesis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hematological Indicators;Carotenoid levels;Oxidative Stress Indicators;Inflammatory Cytokine Indicators;Liver Function Test;Erythrocyte Function Analysis; | — |
Countries
China
Contacts
Public ContactMa Yan
Institute of Nutrition and Health, Qingdao University
Outcome results
None listed