hyoxemia
Conditions
Interventions
Sufentanil group:intravenous injection Sufentanil (0.1 micrograms per kilogram)
Oliceridine group:intravenous injection Oliceridine (20 micrograms per kilogram)
Sponsors
Xiangyang Central Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Agree to participate in this study and sign the informed consent form; 2.ASA grade I to III, age > =18 and =30kg/m²; 3.schedule for hysteroscopic surgery;
Exclusion criteria
Exclusion criteria: 1.There were neuropsychiatric system diseases such as schizophrenia, epilepsy and Parkinson's disease before the operation; 2.Those who are unable to cooperate in completing the preoperative neuropsychological assessment (as assessed by the MMSE scale, those with illiteracy 30); 5.Patients with severely impaired functions of vital organs such as the liver and kidneys, liver and kidney insufficiency (Child-PughB/C or eGFR<30mL/min); 6.Preoperative SpO2<90%;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of severe hypoxemia;Body response during cervical dilation.;Intraoperative respiratory and hemodynamic indicators;postoperative advers events; | — |
Countries
China
Contacts
Public ContactZhang Xiaodong
Xiangyang Central Hospital
Outcome results
None listed