Diminished ovarian function
Conditions
Interventions
experimental group:Liaoshen Sea Cucumber Egg Nano Active Peptide Drink
25mL/bottle
1 bottle per time, once a day
Sponsors
Shengjing Hospital Affiliated to China Medical University.
Eligibility
Sex/Gender
Female
Age
35 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Females aged 35-50 years with a body mass index (BMI) of 18.5-28 kg/m^2; 2. Oligomenorrhea or amenorrhea for 4 months to 1 year; 3. Serum basal follicle-stimulating hormone (FSH) >= 10 U/L (measured at least twice, with an interval of > 4 weeks between tests). Measurements should be performed on days 2-4 of the menstrual cycle, or at any time in cases of amenorrhea. Serum anti-Müllerian hormone (AMH) <= 1.1 ng/mL; 4. Pelvic ultrasonography findings: (1) Normal or slightly reduced uterine size; (2) Bilaterally small ovaries or poorly visualized ovaries; (3) Total number of antral follicles (2-10 mm in diameter) in both ovaries < 5, or absence of visible follicles; 5. All participants must be married and have a normal sexual life; 6. Voluntary participation in the clinical trial, good compliance, and provision of written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with ovarian tumors, endometriosis, or other neoplastic diseases. 2. History of pelvic surgery. 3. Presence of thrombotic disorders or hematological diseases. 4. Severe infection or severe inflammatory response. 5. Cognitive or communication disorders that may interfere with study participation. 6. Cardiac, hepatic, pulmonary, or renal insufficiency. 7. Thyroid dysfunction or other endocrine disorders. 8. Recent use of estrogen- or progesterone-containing medications. 9. Amenorrhea due to causes other than diminished ovarian function (e.g., primary amenorrhea, uterine amenorrhea, pituitary amenorrhea), as well as women who are preparing for pregnancy or breastfeeding. 10. Any other condition that, in the investigator’s judgment, makes the subject unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anti-Müllerian Hormone(AMH);Follicle-Stimulating Hormone(FSH);Luteinizing Hormone;Estradiol;Progesterone;Testosterone;Prolactin; | — |
Countries
China
Contacts
Public ContactBing He
Shengjing Hospital Affiliated to China Medical University
Outcome results
None listed