None
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: 50 - 69 years old, with no history of long-term regular exercise; 2. Normal vision and color vision, able to independently complete all tests and training tasks; 3. Voluntary participation, signing the informed consent form, and being able to fully cooperate with the 8-week intervention; 4. No neurological diseases or mental health history; 5. People with varicose veins in the legs, BMI > 30, hyperlipidemia, etc. can participate with the assessment by doctors and supervision by professionals.
Exclusion criteria
Exclusion criteria: 1. Suffering from severe cardiovascular and pulmonary diseases such as peripheral vascular disease, deep vein thrombosis, heart failure, myocardial infarction, pulmonary embolism, etc. 2. Limb deformity, skin damage / dermatitis, sensory nerve injury, pressure training allergy, pregnant women. 3. Unable to understand or cooperate with training and cognitive tests. 4. Long-term regular exercise before enrollment. 5. Severe joint injury, movement contraindications, drug dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brachial artery flow-mediated dilation (FMD);Inhibitory control of Stroop task (reaction time, accuracy); | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting blood pressure and resting heart rate;Pulse wave velocity (PWV), pulse wave analysis (PWA), heart rate variability (HRV);Working memory performance of N-back task;Cognitive flexibility of Switching task;Body Mass Index (BMI);Prefrontal cortex blood oxygen activation level (fNIRS);Peripheral blood neural, vascular and inflammatory biomarkers (BDNF, Irisin, VEGF, IGF-1, TNF-a); | — |
Countries
China
Contacts
Guangzhou Sport University