Type 2 diabetic neovascular glaucoma
Conditions
Interventions
Group with type 2 diabetes without retinopathy:None
Normal control group:None
Group with type 2 diabetic retinopathy:None
Type 2 diabetes-related neovascular glaucoma group:None
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or over, of any gender, with or without type 2 diabetes and its associated ocular complications; alert and able to cooperate with the iris OCTA examination (able to keep the head still to ensure the examination is completed smoothly and the images are interpretable); 2. Willing to participate in this study and sign a written informed consent form; 3. The eye to be examined must have no history of intraocular surgery (e.g. cataract surgery, glaucoma filtration surgery, retinal surgery, etc.); 4. General medical conditions: no history of acute episodes (such as acute myocardial infarction, stroke or diabetic ketoacidosis) within the past three months; no severe abnormalities in liver or kidney function (ALT and AST <= 2 times the upper limit of normal, serum creatinine <= 133 µmol/L).
Exclusion criteria
Exclusion criteria: 1.The studied eye suffers from other ocular diseases that may interfere with examination results apart from the disorders specified in Criterion 1 of the inclusion criteria (e.g., uveitis, retinal vein occlusion, high myopia-related fundus lesions, etc.); invasive ocular treatments were administered to the studied eye within the past 6 months (e.g., retinal laser photocoagulation, intravitreal injection, etc.); 2.Subjects complicated with type 1 diabetes mellitus, gestational diabetes mellitus or other specific types of diabetes mellitus; those with autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) or hematological diseases (e.g., leukemia, aplastic anemia); individuals who have taken medications affecting ocular microcirculation (e.g., alprostadil, nitrates) within the past 3 months and are unable to discontinue such drugs; 3.Subjects with severe head tremors and inability to maintain a fixed posture during examination, resulting in substandard OCTA image quality (interpretable area < 80%); those with mental disorders or cognitive dysfunction who fail to understand and cooperate with the examination procedures;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vessel Density of Iris;Blood flow fraction at six locations around the iris (superior, superior temporal, inferior temporal, inferior, inferior nasal, and superior nasal) as quantified by OCTA; | — |
Countries
China
Contacts
Public ContactZhang Yuting
Qilu Hospital of Shandong University
Outcome results
None listed