Peri-extubation hypoxemia in patients with early gastrointestinal neoplasms undergoing ESD
Conditions
Interventions
Supine Position Group:xtubation in Supine Position
Lateral Position Group:Extubation in Lateral Position
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Scheduled for elective Endoscopic Submucosal Dissection (ESD); 2.Aged 18 to 65 years; 3.American Society of Anesthesiologists (ASA) physical status class I to III; 4.Planned and received general anesthesia with endotracheal intubatio; 5.Signed written informed consent obtained from the patient or their legal representative;
Exclusion criteria
Exclusion criteria: 1.Anticipated difficult airway (e.g., Mallampati class IV, mouth opening 40 cm (male) /38 cm (female)); 2.High risk of aspiration/reflux (e.g., non-fasting, severe obesity BMI>35 kg/m², symptomatic GERD or hiatal hernia); 3.Severe cardiopulmonary disease (e.g., NYHA class III-IV, severe COPD); 4.Contraindication to position change (e.g., severe spinal deformity); 5.Coagulopathy or high risk of bleeding; 6.Emergency surgery, increased intracranial pressure, multiple trauma; 7.Preoperative systolic blood pressure <80 mmHg or resting SpO2 <94% on room air;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia within 10 minutes after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of severe hypoxemia;ost-Anesthesia Care Unit (PACU) length of stay;Minimum oxygen saturation;Incidence of postoperative nausea and vomiting (PONV);Patient comfort;Modified Cough Score;Hemodynamic stability;Richmond Agitation-Sedation Scale (RASS) score; | — |
Countries
China
Contacts
Public ContactXifeng Wang
The first affiliated hostipal of nanchang university
Outcome results
None listed