Biliary obstruction,biliary stricture, pancreatic duct stricture
Conditions
Interventions
Sufentanil group (control group):Sufentanil
Esketamine group (intervention group):Esketamine
Sponsors
Beijing Friendship Hospital ,Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients undergoing ERCP; 2. ASA physical status I–III; 3. Age >=18 years; 4. BMI 18.5–30 kg/m^2; 5. Voluntary participation with signed informed consent;
Exclusion criteria
Exclusion criteria: 1. Severe hypertension (grade 3 or above; >=180/110 mmHg); 2. Severe cardiac, pulmonary, hepatic, or renal dysfunction; 3. History of central nervous system or psychiatric disorders; 4. Difficult airway; 5. Known allergy to study drugs; 6. Patients requiring general anesthesia with endotracheal intubation, or conversion to general anesthesia with intubation intraoperatively;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypotension;Sedation and procedure-related indicators;Respiratory and circulatory indicators;Perioperative adverse events;Medication and recovery indicators; | — |
Countries
China
Contacts
Public ContactRen Da
Beijing Friendship Hospital ,Capital Medical University
Outcome results
None listed