Skip to content

How Adipose Tissue Affects Heart Function: A Metabolic Story

Adipocyte Metabolism and Cardiac Function: Mechanisms and Implications

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128640
Enrollment
Unknown
Registered
2026-07-23
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary atherosclerotic heart disease, also known as coronary heart disease

Interventions

Preserved LVEF Group:None
Reduced LVEF Group:None

Sponsors

The Second Affiliated Hospital Of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Age range: 18 to 85 years old, gender unrestricted; 2.Clinically diagnosed with coronary heart disease (including chronic stable angina, unstable angina, etc.) in a secondary or higher-level hospital (based on clinical diagnosis certificate/medical record); 3.Voluntary participation in this study and signing the informed consent form; 4.Clear consciousness and able to cooperate with general surveys, blood sample collection, and operations such as cardiac ultrasound and vascular CT examinations;

Exclusion criteria

Exclusion criteria: 1.Refusal to sign the informed consent form; 2.Coexistence of severe liver and kidney failure, malignant tumors, severe infectious diseases, severe trauma, and acute phase of autoimmune diseases; 3.Presence of obvious mental disorders or cognitive impairments, making it impossible to cooperate with the research process; 4.Pregnant or lactating women; 5.Within the past 3 months, having undergone major surgery or having severe trauma; 6.Insufficient clinical data, making it impossible to clearly diagnose coronary heart disease; 7.Complicated with other serious cardiovascular diseases that affect the determination of research results;

Design outcomes

Primary

MeasureTime frame
Levels of Adipokines and Inflammatory Cytokines (Adiponectin, Leptin, IL-6, TNF-a etc.);IL-6;Evaluation of cardiac function;Degree of coronary artery stenosis and Agatston calcification score;

Secondary

MeasureTime frame
Myocardial Enzymes and Cardiac Biomarkers;

Countries

China

Contacts

Public ContactLi Tianzi

The Second Affiliated Hospital Of Zhengzhou University

tz398180418@163.com+86 371 63974868

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026