Pulpitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 to 25 years, regardless of gender. 2.Patients requiring extraction of impacted third molars.
Exclusion criteria
Exclusion criteria: 1.Presence of dental or periodontal disease on clinical examination. 2.Radiographs show root developmental anomalies or periapical lesions; 3.Patients with systemic diseases; 4.Contraindications to tooth extraction, including: Cardiac conditions: history of MI within 6 months or angina symptoms Hypertension: BP >180/100 mmHg Anemia: Hb usually 8.88 mmol/L Bleeding disorders, etc. 5. Women or lactating women; 6. People with mental or intellectual disabilities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of CeO2@mCS on the activity of dental pulp stem cells;The effect of CeO2@mCS on the odontogenic/osteogenic differentiation of dental pulp stem cells;The effect of CeO2@mCS drug-free or drug-loaded on the antioxidant stress of dental pulp stem cells;Changes in anti-inflammatory and odontogenic/osteogenic differentiation-related indicators of dental pulp stem cells.; | — |
Countries
China
Contacts
Beijing Stomatological Hospital , Capital Medical University