Skip to content

A real-world prospective, multicenter clinical study of furmonertinib in the adjuvant treatment of stage IA2-IIIA EGFR mutation-positive non-small cell lung cancer after surgery

A real-world prospective, multicenter clinical study of furmonertinib in the adjuvant treatment of stage IA2-IIIA EGFR mutation-positive non-small cell lung cancer after surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128622
Enrollment
Unknown
Registered
2026-07-23
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-Small Cell Lung Cancer

Interventions

Observation group:None

Sponsors

The Fourth Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Obtain the patient's written informed consent; 2. Male or female, aged >= 18 years; 3. Pathological stage IA2-IIIA NSCLC (IASLC 9th Edition); 4. Patients with stage IA2 and IA3 must have at least one high-risk factor. High-risk factors include: pathological tissue types containing high-grade components [solid pattern, micropapillary pattern, cribriform and/or complex glandular structures], vascular invasion, vascular tumor thrombus, nerve invasion, and spread through air spaces (STAS); 5. Positive for EGFR-sensitive mutations (19del and/or L858R mutation, with or without T790M mutation), which must be confirmed by tumor tissue analysis; 6. After R0 resection of lung cancer; 7. Have received furmonertinib treatment.

Exclusion criteria

Exclusion criteria: 1. Prior receipt of treatment with other EGFR-TKIs; 2. History of other malignant tumors, or concurrent other malignant tumors at present (except for malignant tumors that have undergone radical resection and have not recurred for 5 years after surgery, such as carcinoma in situ of the cervix, basal cell carcinoma of the skin, and papillary thyroid carcinoma, etc.); 3. Current pregnancy or lactation; 4. Other conditions that the investigator deems unsuitable for participation in this study.

Design outcomes

Primary

MeasureTime frame
3-year Disease-Free Survival rate;

Secondary

MeasureTime frame
Disease-Free Survival, DFS;2-year Disease-Free Survival rate;2-year and 3-year overall survival rates;

Countries

China

Contacts

Public ContactWang Hongyan

The Fourth Hospital of Hebei Medical University

tiger_wt@sina.com+86 311 86095588

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026