Radiotherapy leads to reproductive endocrine damage
Conditions
Interventions
Experimental group:Uterine Adnexal Displacement and Repositioning
Sponsors
Obstetris & Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
14 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged less than 45 years; 2. Normal BMI range: 18.5-24.9; 3. The length and diameter of the uterus are less than 12cm, and there are no obvious uterine-related diseases. No extensive or severe endometriosis; 4. The primary disease (such as colorectal cancer) has not involved the uterus, cervix, vagina or ovaries. Through the MDT multidisciplinary consultation, the consent of the primary disease treatment team was obtained. In cases where pelvic radiotherapy is required or other situations where the uterus and/or adnexa need to be displaced; 5. Informed consent, willingness to be enrolled, and consent to assist in completing all follow-up visits.
Exclusion criteria
Exclusion criteria: 1. Suffering from acute or severe infectious diseases (such as AIDS, syphilis, etc.); 2. Other circumstances that do not comply with the law or ethics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reproductive endocrine hormone;Uterine and ovarian dimensions and vascularity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resumption of menstrual function; | — |
Countries
China
Contacts
Public ContactZhang Ying
Obstetris & Gynecology Hospital of Fudan University
Outcome results
None listed