Critical and emergency conditions, including sepsis, acute stroke, acute myocardial infarction, ARDS, pulmonary embolism, cardiac arrest, acute aortic dissection, acute poisoning, etc.
Conditions
Interventions
Critical and Severe Illnesses:None
Sponsors
Shanghai Minhang District centeral hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Aged >= 18 years old, regardless of gender; 2.Meet the latest international diagnostic criteria for specific critical illnesses (e.g., Sepsis-3); 3.Expected ICU length of stay = 48 hours; 4.The patient or their legal representative agrees to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Aged < 18 years old; 2.End-stage malignant tumors; 3.Long-term administration of high-dose immunosuppressants or cytotoxic drugs prior to enrollment; 4.Severe primary immunodeficiency diseases or hematological malignancies; 5.Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary clinical endpoint: A total of no less than 300 eligible subjects shall be enrolled; | — |
Secondary
| Measure | Time frame |
|---|---|
| 28-day and 90-day all-cause mortality; | — |
Countries
China
Contacts
Public ContactSun Keyu
Shanghai Minhang District centeral hospital
Outcome results
None listed