Acute and chronic pain following surgery for trunk or limb fractures in adults
Conditions
Interventions
group C:Intraoperative intravenous infusion of 0.9% normal saline .
group L:Intraoperative intravenous infusion of lidocaine
Sponsors
Yiling Hospital Of Yichang City
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18–65 years; 2. ASA classification II–III; 3. Patients requiring internal fixation due to limb fractures or spinal trauma and scheduled for surgical intervention at Yiling Hospital; 4. The patient or their legally authorized representative has signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with comorbid conditions that are not adequately controlled, such as hypertension, diabetes, chronic pain, epilepsy, asthma, renal impairment (BUN and/or Cr > twice the normal value), or hepatic impairment (ALT and/or AST > 1.5 times the normal value); 2. Patients with traumatic brain injury or severe visceral injuries—including visceral rupture, shock, or other critical conditions—as well as those with severe infections or sepsis; 3. Patients requiring emergency surgery, such as those with puncture wounds, blast injuries, gunshot wounds, or stab wounds; 4. Patients allergic to any component of anesthetic agents or with confirmed or suspected history of opioid abuse; 5. Patients undergoing surgery lasting less than 30 minutes or exceeding 180 minutes; 6. Patients who refuse, disagree with, or cannot comprehend the study protocol; 7. Patients with other conditions deemed unsuitable by investigators for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| First functional exercise session duration;postoperative pain scores;chronic pain scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative opioids consumption;Postoperative nausea and vomiting;Time of first meal;Time required for intestinal ventilation to recover;Hemodynamic parameters (hypertension, hypotension, tachycardia, bradycardia);postoperative analgesic medications consumption;Post-anesthetic sedation score; | — |
Countries
China
Contacts
Public ContactJiang Hongying
Yiling Hospital Of Yichang City
Outcome results
None listed