Colorectal tumour
Conditions
Interventions
Low-volatility group:None
Medium-wave group:None
High-volatility group:None
Sponsors
Meizhou People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients who are able to understand the study content and cooperate in completing the postoperative quality of recovery assessment; 2.Undergoing elective laparoscopic colorectal surgery; 3.Preoperative American Society of Anesthesiologists (ASA) physical status classification I–III, with relatively stable overall vital signs; 4.Scheduled to undergo surgery under total intravenous anesthesia, with dexmedetomidine used as an adjuvant medication during the anesthesia maintenance phase; 5.Complete routine intraoperative monitoring conditions are in place, allowing continuous and complete acquisition of hemodynamic data such as blood pressure and heart rate; 6.Able to complete the QoR-15 scale assessment within the specified time period after surgery; 7.Agree to the content of this clinical study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Preoperative presence of severe cardiovascular diseases, such as uncontrolled hypertension, severe arrhythmias, or significant cardiac insufficiency, which may significantly interfere with hemodynamic stability; 2.Concomitant severe hepatic or renal dysfunction, or endocrine system diseases that affect drug metabolism or stress response; 3.Intraoperative conversion to open surgery or occurrence of severe complications, causing the anesthesia and surgical process to deviate significantly from the routine pathway; 4.Occurrence of critical events requiring special intervention during surgery, such as severe hypotension or malignant arrhythmias; 5.Perioperative use of sedatives, analgesics, or vasoactive agents outside the study protocol, affecting the comparability of hemodynamic assessments; 6.Inability to complete the QoR-15 scale assessment postoperatively for various reasons, or missing data. By strictly excluding the above conditions, the influence of potential confounding factors on the study results will be reduced.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 total score at 24 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of surgery;Incidence of Postoperative Nausea and Vomiting (PONV);Postoperative analgesic requirements; | — |
Countries
China
Contacts
Public ContactShi Liang
Meizhou People's Hospital
Outcome results
None listed