Kidney injury, acute respiratory distress syndrome (ARDS), poisoning, and acid-base and electrolyte imbalances
Conditions
Interventions
Citrate-4.0:Regional citrate anticoagulation using citrate-4.0 during continuous kidney replacement therapy
Citrate-3.5:Regional citrate anticoagulation using citrate-3.5 during continuous kidney replacement therapy
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; 2.Planned to receive renal replacement therapy with an expected treatment duration of =8 hours;
Exclusion criteria
Exclusion criteria: 1.Severe hepatic dysfunction, defined as Child-Pugh class B or higher; 2.Patients with multiple thromboembolic diseases requiring heparin anticoagulation; 3.Pregnant or lactating women; 4.Patients who refuse to participate in this study; 5.Patients participating in other interventional studies at the same time;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clotting-free filter survival time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolic Alkalosis;Metabolic Acidosis;Hypercalcemia;Hypocalcemia;Metabolic Alkalosis;Filter lifespan;Systemic ionized calcium concentration;Bicarbonate concentration;pH;Base excess;Lactate concentration;Serum sodium concentration;Serum total calcium concentration; | — |
Countries
China
Contacts
Public ContactTingting
Xuanwu Hospital Capital Medical University
Outcome results
None listed