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Clinical Evaluation of Oxaliplatin-Based Doublet Regimens as Adjuvant Therapy for Gastroenteric Neuroendocrine Carcinoma: Efficacy and Safety

Clinical Evaluation of Oxaliplatin-Based Doublet Regimens as Adjuvant Therapy for Gastroenteric Neuroendocrine Carcinoma: Efficacy and Safety

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128531
Enrollment
Unknown
Registered
2026-07-22
Start date
2026-04-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal neuroendocrine tumors

Interventions

XELOX (oxaliplatin combined with capecitabine) :None

Sponsors

Chinese Academy of Medical Sciences, Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed as gastrointestinal neuroendocrine carcinoma by histopathological examination; 2. Patients who have undergone radical tumor resection regardless of the stage; 3. Gender not limited, aged 18-75 years old; 4. Eastern Cooperative Oncology Group (ECOG) performance status score: = 3 months; 6. Agree to undergo testing, treatment and follow-up in accordance with this research protocol, agree to provide the clinical pathology and follow-up data required by this study, and agree to use the data from this study for subsequent research; 7. Voluntarily participate in this clinical study, understand the research procedures and be able to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Participants were excluded if they had any other malignant tumors within the previous 5 years. 2. Participants were excluded if they had received any anti-tumor treatment within the previous 6 months. 3. According to the investigator's judgment, there were serious accompanying diseases (such as poorly controlled hypertension, severe diabetes, thyroid disorders, and mental illnesses, etc.) or any other conditions that could seriously endanger the safety of the patients or affect their ability to complete this study.

Design outcomes

Primary

MeasureTime frame
Disease-Free Survival (DFS);

Secondary

MeasureTime frame
Overall Survival (OS);Side effects;

Countries

China

Contacts

Public ContactYou tingting

Chinese Academy of Medical Sciences, Peking Union Medical College Hospital

2667518859@qq.com+86 10 6915 8766

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026