Acute postoperative pain after gynecologic surgery
Conditions
Interventions
Non-high oliceridine consumption group:None
High oliceridine consumption group:None
Sponsors
Quanzhou first Hospital,Fujian
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years, female; 2. Undergo elective gynecological surgery, including hysterectomy, adnexal surgery, myomectomy, radical gynecological oncology surgery, and other related gynecological procedures; 3. Postoperative use of Oliceridine fumarate PCIA; 4. ASA physical status I to III; 5. PCIA use duration >=48 hours, or at least complete records of cumulative dosage within 48 hours postoperatively; 6. Electronic medical records, anesthesia records, nursing records, and APS follow-up data are basically complete.
Exclusion criteria
Exclusion criteria: 1. Preoperative chronic pain, regular opioid use, or confirmed opioid tolerance; 2. Severe psychiatric disease or cognitive impairment affecting reliable pain assessment; 3. Postoperative use of other continuous strong opioid analgesic regimens that may interfere with the assessment of actual oliceridine requirement; 4. PCIA use for less than 48 hours; 5. Early discontinuation of PCIA due to severe adverse reactions; 6. Severe missing data in key variables; 7. Reoperation or major postoperative complications within 48 hours after surgery that may substantially affect analgesic requirement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative oliceridine fumarate consumption within 48 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of rescue analgesia within 48 hours after surgery;Postoperative length of hospital stay;Occurrence of postoperative nausea and vomiting within 48 hours after surgery;Resting and movement NRS scores on postoperative day 1 and day 2;Adverse events within 48 hours after surgery; | — |
Countries
China
Contacts
Public ContactChen Dandan
Quanzhou first Hospital,Fujian
Outcome results
None listed