Spinal tuberculosis
Conditions
Interventions
Non-sclerotic bone group:None
Fragmented sclerotic bone group:None
Non-fragmented sclerotic bone group:None
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with spinal tuberculosis in the outpatient department and scheduled for surgical treatment; 2. This hospitalization is the first time to receive anti-tuberculosis chemotherapy; 3. Aged 18 to 60 years old; 4. American Society of Anesthesiologists (ASA) classification: Grade I-III; 5. Body Mass Index (BMI, Kg/m^2) between 18 and 30; 6. Those who voluntarily join this research and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Drug-resistant tuberculosis; 2. Patients with a history of spinal surgery or those with other concurrent spinal diseases; 3. Patients with severe damage to important organs such as the heart, liver, brain, lungs, and kidneys; 4. Pregnant or lactating women, or those with severe mental illnesses; 5. Patients with diabetes whose blood glucose control has not reached the target (fasting blood glucose >11.1 mmol/L, glycated hemoglobin >8.0%) or those with diabetic complications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The concentration of anti-tuberculosis drugs in the lesion; | — |
Secondary
| Measure | Time frame |
|---|---|
| The concentration of anti-tuberculosis drugs in the blood; | — |
Countries
China
Contacts
Public ContactDu Xing
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed