Skip to content

Clinical study on the dose-effect relationship of ropivacaine spinal anesthesia at different temperatures for cesarean delivery

Clinical study on the dose-effect relationship of ropivacaine spinal anesthesia at different temperatures for cesarean delivery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600128512
Enrollment
Unknown
Registered
2026-07-21
Start date
2025-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Combined spinal-epidural anesthesia for labor

Interventions

Room temperature group (24?):Using room temperature (24?) 0.5% heavy bupivacaine for combined spinal-epidural block in term pregnant women.
Body temperature group (37?):Use of 0.5% heavy bupivacaine at body temperature (37?) for combined spinal-epidural block in term pregnant women

Sponsors

Jiaxing Maternal and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. The study subjects were full-term (i.e., =37 weeks) singleton primiparous patients with an American Society of Anesthesiologists (ASA) physical status classification of II, who were scheduled for lower uterine segment cesarean delivery; 2. All included patients voluntarily participated in the study and signed informed consent forms.

Exclusion criteria

Exclusion criteria: 1. Patients with preeclampsia, hypertension or gestational hypertension; 2. Body mass index (BMI) >35kg/m^2; 3. Cardiovascular and cerebrovascular diseases; 4. Diabetes or gestational diabetes; 5. Multiple pregnancy; 6. Placenta previa; 7. Fetal distress; 8. Suspected fetal intrauterine growth restriction; 9. Contraindications to neuraxial anesthesia; 10. Allergic to bupivacaine; 11. Refused to participate in the study.

Design outcomes

Primary

MeasureTime frame
Effective or ineffective subarachnoid block;

Secondary

MeasureTime frame
Record patients’ demographic information.;Record the patient’s intrathecal bupivacaine dosage.;Record the number of interventions by the anesthesiologist;Record the surgical procedure time;Record whether adverse reactions such as hypertension, hypotension, bradycardia, nausea, vomiting, and chills occur.;Record the newborn’s Apgar scores at 1 and 5 minutes.;Record the onset and offset times of sensory blockade and motor blockade in the patient.;Record patient satisfaction and the chief surgeon’s satisfaction.;Record fetal umbilical artery blood pH value;

Countries

China

Contacts

Public ContactZhao Yanping

Jiaxing Maternal and Child Health Care Hospital

491057876@qq.com+86 159 0673 4047

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026