Pain
Conditions
Interventions
Group Oxycodone:Intravenous oxycodone 0.3 mg/kg was administered for anesthesia induction, and intravenous oxycodone 0.1 mg/kg was injected at the time of the final skin suture.
Group Sufentanil:Intravenous sufentanil 0.3 µg/kg was given during anesthesia induction, with intravenous sufentanil 0.1 µg/kg injected upon placement of the last skin suture.
Sponsors
Second Affiliated Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients scheduled for thoracoscopic pulmonary wedge resection under general anesthesia with endotracheal intubation; 2.Aged 18 to 70 years old, no gender restriction; 3.Body mass index (BMI) ranging from 18 kg/m² to 30 kg/m²; 4.American Society of Anesthesiologists (ASA) physical status classification II–III; 5.Voluntarily signed informed consent form;
Exclusion criteria
Exclusion criteria: 1.Presence of chronic pain; 2.Presence of severe cardiovascular diseases; 3.Presence of severe respiratory diseases or other severe systemic diseases; 4.History of gastrointestinal bleeding or peptic ulcer within the past 2 months; 5.Dependence on alcohol or opioids; 6.Long-term use of other psychotropic drugs; 7.Allergy to any medications used in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative VAS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Analgesic Drug Usage;Recovery time;Levels of inflammatory factors including IL-6, TNF-a and CRP;Incidence of adverse reactions;Ramsay sedation scale;Postoperative pulmonary complications;Postoperative length of hospital stay; | — |
Countries
China
Contacts
Public ContactYongfa Zhang
Second Affiliated Hospital of Shantou University Medical College
Outcome results
None listed