Skip to content

Clinical Value of an AI-Based Dynamic Early Warning System-Assisted Approach for Early Recognition and Intervention of Multiple Organ Dysfunction in ICU Patients: A Multicenter, Prospective, Randomized, Parallel-Controlled Trial

Clinical Value of an AI-Based Dynamic Early Warning System-Assisted Approach for Early Recognition and Intervention of Multiple Organ Dysfunction in ICU Patients: A Multicenter, Prospective, Randomized, Parallel-Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600128504
Enrollment
Unknown
Registered
2026-07-21
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple organ dysfunction

Interventions

Trial group:In anticipation of the possibility of multiple organ dysfunction, clinical intervention will be carried out in advance.
Control group:None

Sponsors

Pudong New Area People's Hospital, Shanghai
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old, gender not restricted; 2. Admitted to the ICU and undergoing continuous monitoring of vital signs and routine laboratory tests; 3. Expected ICU stay time >= 24 hours, with the conditions to continuously observe the risk of multiple organ dysfunction; 4. At the time of enrollment, did not meet the criteria for multiple organ dysfunction; 5. The quality of vital sign monitoring data meets the standard and can be used for real-time analysis by the AI system; 6. The subject or their legal representative signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1. They already had clear multi-organ dysfunction at the time of enrollment; 2. Their expected ICU stay is less than 24 hours or they are about to be transferred out of the ICU; 3. Patients with end-stage diseases or those who have decided to abandon active treatment; 4. There is severe data missing or the monitoring equipment is unable to reliably obtain key data; 5. They are participating in other interventional clinical trials that may affect the main endpoint of this study; 6. Other situations that the investigator deems unsuitable for inclusion in this study.

Design outcomes

Primary

MeasureTime frame
Continuous vital signs monitoring data;Laboratory index;Clinical interventions;Clinical outcome;

Countries

China

Contacts

Public ContactWan Jian

Pudong New Area People's Hospital, Shanghai

wanjian@shpdph.cn+86 136 8197 8927

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026