Acute kidney injury (AKI) is defined as an abrupt decline in renal function that includes a rapid increase in serum creatinine (sCr), decrease in urine output (UO), or both.
Conditions
Interventions
Gold Standard:According to the criteria established by the Kidney Disease: Improving Global Outcomes (KDIGO) classification, AKI is staged by serum creatinine and urine output changes: Stage 1 involv
Index test:All ultrasound examinations were performed using a Vinno ULTIMUS 9E Super ultrasound system (Vinno Medical, Suzhou, China) equipped with software version 1.51.31 (BK1). The ultrasound contr
Bracco Imaging S.p.A., Milan, Italy) was used. The lyophil
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. First-time recipients of allogeneic kidney transplantation, including those receiving grafts from living donors or deceased donors; 2. Aged >= 18 years.
Exclusion criteria
Exclusion criteria: 1. Patients receiving multi-organ combined transplantation; 2. Patients who have undergone two or more kidney transplantations, or bilateral kidney transplantation (mostly recipients of pediatric donor kidneys); 3. Patients with a previous history of malignant tumors; 4. Patients with severe failure of other organs (e.g., heart, liver, lung, etc.); 5. Patients with contraindications to ultrasound contrast agents; 6. Pregnant or breastfeeding women; 7. The distance from the capsule of the middle or lower pole of the renal allograft to the skin exceeds 2.5 cm; 8. Renal allograft hydronephrosis >= 2 cm, or moderate to large peritransplant fluid collection with the maximum depth of fluid >= 2 cm, which is caused by complications including urinary tract obstruction, urinoma (urinary leakage within the first 2 weeks after transplantation), lymphocele (4–8 weeks after transplantation), perinephric infection, etc.; 9. Patients who fail to cooperate, those with unsatisfactory image acquisition, or cases with missing clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AKI;Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactJiaojiao Zhou
West China Hospital of Sichuan University
Outcome results
None listed