Endometrial polyps
Conditions
Interventions
Hysteroscopic cold knife morcellation group :None
Hysteroscopic electrosurgery group:None
Sponsors
Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 20–45 years with fertility requirements or a desire to preserve reproductive function; 2. Initially diagnosed by transvaginal ultrasound and confirmed as endometrial polyps (EPs) via hysteroscopy; 3. Polyp diameter =1.0 cm, or <1.0 cm but causing significant clinical symptoms (e.g., abnormal uterine bleeding, infertility); 4. Signed informed consent and willingness to undergo postoperative follow-up; 5. Pathologically confirmed as having endometrial polyps.
Exclusion criteria
Exclusion criteria: 1. Patients with postoperative pathological diagnosis of submucosal uterine fibroids, endometrial atypical hyperplasia, or endometrial malignant lesions; 2. Patients with severe medical conditions (e.g., cardiac, hepatic, or renal dysfunction) or coagulation disorders that increase surgical risk; 3. Patients with a recent history (e.g., within 3 months) of hormone therapy (e.g., progesterone, GnRH-a); 4. Patients with uterine abnormalities detected by ultrasound or during surgery, such as uterine septum, intrauterine or cervical adhesions, or stenosis; 5. Patients lost to follow-up, or with missing key clinical or follow-up data; 6. Patients in special physiological states: pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VEGF level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Polyps recurrence ;intrauterine adhesions assessed during a second hysteroscopy (using the AFS scoring system); | — |
Countries
China
Contacts
Public ContactGengHua Fu
Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed