Cancer patients who are receiving chemotherapy treatment with taxanes and platinum-based drugs
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age:>=18 years old; 2. Diagnosis:Solid tumors including breast cancer, colorectal cancer and gastric cancer; 3. Chemotherapy regimen: The patient is scheduled to receive at least 12 weeks of treatment with any of the following agents: taxanes, oxaliplatin; 4. CIPN Baseline: No or mild neurotoxicity, FACT/GOG-Ntx neurotoxicity subscale score >=36/44; 5. ECOG:0-2; 6. Expected Survival: >=6 months; 7. Informed Consent: Voluntary Signature.
Exclusion criteria
Exclusion criteria: 1. CIPN:FACT/GOG-Ntx 8.0% or pre-existing diabetic peripheral neuropathy; 3. Alcohol abuse: average daily alcohol consumption over the past 6 months is more than 3 standard drinks; 4. Vitamin Deficiency It is well established that deficiencies in vitamin B1, B6, B12 or folate remain uncorrected. 5. Metallic Implants: Cardiac Pacemakers, Defibrillators, Aneurysm Clips, Internal Fixation Devices; 6. Pregnancy/Lactation; 7. Comprehension Impairment: Inability to complete the questionnaire.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FACT/GOG-Ntx; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life (QoL);Chemotherapy Dose Maintenance Rate; | — |
Countries
China
Contacts
Peking Union Medical College Hospital