Postoperative Pulmonary Injury Following Cardiac Surgery
Conditions
Interventions
conventional group:peep was set according to a standard protocol based on blood gas analysis, oxygenation index and lung compliance
ultrasound-guided group:Dynamic Adjustment of PEEP Based on Multimodal Parameters from Bedside Ultrasound
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective cardiac surgery (such as mitral valve replacement, aortic valve replacement, etc.) who require mechanical ventilation postoperatively; 2. Age >= 18 years; 3. No history of severe pulmonary arterial hypertension (pulmonary artery systolic pressure <= 50 mmHg), end-stage lung disease, or acute respiratory failure prior to surgery. 4. Patients who agree to participate in the trial and have signed an informed consent form
Exclusion criteria
Exclusion criteria: 1.patients undergoing emergency surgery or requiring extracorporeal membrane oxygenation (ecmo) support preoperatively; 2.patients with severe hepatic and renal insufficiency, malignant tumor, or immunosuppressive status; 3.patients with severe intraoperative complications (e.g., massive hemorrhage, cardiac arrest);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of pulmonary complications within 5 days postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of ICU stay after surgery;Duration of mechanical ventilation in ICU;arterial partial pressure of carbon dioxide;dynamic lung compliance;central venous pressure;Oxygenation Index;28-day all-cause mortality;Partial Pressure of Arterial Oxygen; | — |
Countries
China
Contacts
Public ContactBu Lin
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed