Parathyroid autotransplantation
Conditions
Interventions
Parathyroid sternocleidomastoid muscle transplantation group:Autologous parathyroid tissue is injected into the contralateral sternocleidomastoid muscle via multi-point (three-point) homogenisation
Forearm brachioradial autologous parathyroid transplantation group :Autologous parathyroid gland transplantation via multi-point (three-point) homogenised injection into the brachioradialis muscle of
Sponsors
Kunming Yan'an Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 and 65 years; 2. Adult patients with a pathologically confirmed diagnosis of papillary thyroid carcinoma who are scheduled to undergo bilateral total thyroidectomy combined with central lymph node dissection; 3. Patients who are aware of the details of this study and have voluntarily signed an informed consent form; 4. No history of head and neck surgery or radiotherapy; 5. Patients in whom a single inferior parathyroid gland is found during surgery to have poor blood supply, cannot be preserved in situ or has been inadvertently resected, and who are confirmed via parathyroid immunogold labelling to require autologous parathyroid transplantation.
Exclusion criteria
Exclusion criteria: 1. Patients with organ dysfunction or who are unable to tolerate surgery; 2. Patients requiring reoperation due to recurrence in the central lymph nodes following surgery; 3. Patients who are unable to attend follow-up appointments on time or who are lost to follow-up; 4. Patients requiring postoperative radioactive iodine therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum parathyroid hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum calcium;Additional calcium intake rate;Incidence of symptoms associated with low calcium levels;Pain score;Patient satisfaction scores; | — |
Countries
China
Contacts
Public ContactRao Jianfa
Kunming Yan'an Hospital
Outcome results
None listed