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40 Hz Flickering Light for the Prevention of Postpartum Depression After Cesarean Section: A Randomized, Double-Blind, Placebo-Controlled Trial

40 Hz Flickering Light for the Prevention of Postpartum Depression After Cesarean Section: A Randomized, Double-Blind, Placebo-Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600128364
Enrollment
Unknown
Registered
2026-07-19
Start date
2026-07-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum depression (PPD)

Interventions

Intervention group:40 Hz flickering light. Participants received the intervention in a dimly lit environment in the post-anesthesia care unit (PACU) or ward. Participants wore a 40 Hz flickering ligh
Control group:White light therapy. The intervention environment, procedures, and timing schedule in the sham group were identical to those in the active intervention group. Participants wore the same

Sponsors

Huzhou Maternity & Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.Age between 18 and 45 years; 2.Gestational age of at least 34 weeks; 3.American Society of Anesthesiologists (ASA) physical status classification of I–III; 4.Ability to comprehend study procedures and rating instruments, and to communicate effectively with research personnel; 5.Willingness to participate, documented by provision of written informed consent.

Exclusion criteria

Exclusion criteria: 1.Severe obstetric complications, including severe preeclampsia, placenta accreta, HELLP syndrome, placenta previa, or placental abruption; 2.Refractory or persistent hypertension, severe cardiovascular disease (New York Heart Association functional class III or above), or hyperthyroidism; 3.Concurrent use of medications known to influence mood or prescribed for the management of mood-related disorders; 4.Clinically significant disorders of the visual system, encompassing glaucoma, severe retinal pathology, marked optic neuropathy, severe visual impairment, or photosensitive ocular conditions; 5.A documented history of epilepsy or photosensitive migraine disorder; 6.Severe systemic illness, active suicidal ideation, or a self-reported history of major psychiatric disorders—including bipolar disorder and schizophrenia—or ongoing psychiatric treatment with anxiolytics, psychotropic agents, or formal psychotherapy.

Design outcomes

Primary

MeasureTime frame
Incidence of postpartum depression at 6 weeks;

Secondary

MeasureTime frame
severity of postpartum blues (PPB);Rescue analgesia;Postoperative sleep quality;Postoperative pain and cumulative opioid consumption;Severity of postpartum depression (PPD);Adverse events and complications;

Countries

China

Contacts

Public ContactCheng Qian

Huzhou Maternity & Child Health Care Hospital

438273397@qq.com+86 572 2030248

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026