Fractures requiring hip replacement
Conditions
Interventions
Stimulation Group:Percutaneous auricular vagus nerve stimulation
Sham stimulation group:Percutaneous auricular vagus nerve Sham stimulation
Sponsors
The Affiliated Hospital of Yangzhou University
Eligibility
Sex/Gender
All
Age
65 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years; 2. ASA classification levels I–III; 3. Scheduled for elective semi-total or total hip arthroplasty; 4. The patient voluntarily participates and signs an informed consent form, understands the study protocol and assessment scales, and has effective communication skills.
Exclusion criteria
Exclusion criteria: 1. Presence of a clear neurological or psychiatric disorder in the medical history (e.g., Alzheimer's disease, Parkinson's disease, schizophrenia, etc.), or ongoing use of corresponding therapeutic medications; 2. Preoperative cognitive impairment (MMSE score <23); 3. Lesions such as dermatitis, rash, infection, or trauma on the left auricle; 4. Treatment-resistant arrhythmia, preoperative resting heart rate <50 beats/min, sick sinus syndrome, second-degree or higher atrioventricular block, or implantation of a cardiac pacemaker; 5. Recent (within 1 month) use of cholinergic drugs, anticholinergic drugs, or glucocorticoids; 6. History of neurosurgical surgery, severe hearing or visual impairment, opioid abuse, participation in other clinical trials within the past 30 days, or illiteracy; 7. Other circumstances deemed unsuitable by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 Total Score (Range: 0–150 points); | — |
Countries
China
Contacts
Public ContactWang Maohua
The Affiliated Hospital of Yangzhou University
Outcome results
None listed