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A Prospective Cohort Study on the Impact of Uvulopalatopharyngoplasty on Cognitive Function in Patients with Obstructive Sleep Apnea

A Prospective Cohort Study on the Impact of Uvulopalatopharyngoplasty on Cognitive Function in Patients with Obstructive Sleep Apnea

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128291
Enrollment
Unknown
Registered
2026-07-17
Start date
2026-07-20
Completion date
Unknown
Last updated
2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea

Interventions

The cohort of patients who underwent UPPP surgery:None

Sponsors

The Third Affiliated Hospital Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age range: 18 - 70 years old. 2.Diagnosed with OSA through overnight polysomnography (PSG). 3.Evaluated by otolaryngology department and found to have anatomical upper airway stenosis, meeting the indications for UPPP surgery and planning to undergo the surgery. 4.Voluntarily participated in the study and signed the written informed consent form.

Exclusion criteria

Exclusion criteria: 1. There is a clear previous diagnosis of major mental and neurological disorders such as dementia, schizophrenia, bipolar disorder, etc. 2. Other neurological diseases that cause cognitive decline, such as stroke, brain tumor, Parkinson's disease, epilepsy, post-traumatic sequelae of brain injury, etc. 3.Having chronic sinusitis, nasal polyps, acute exacerbation of allergic rhinitis, or a history of nasal and sinus surgery may seriously affect the results of the olfactory test. 4.Having severe or unstable internal medical conditions, such as heart failure classified as NYHA Class III-IV, severe chronic obstructive pulmonary disease, liver and kidney failure, active malignant tumors, etc. 5.Long-term heavy alcohol consumption (equivalent to ethanol intake > 40 grams per day) or history of drug abuse. 6.Having visual, hearing or language impairments, making it impossible to cooperate in completing neuro-psychological assessments. 7.Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Cognitive score;

Secondary

MeasureTime frame
Sense of smell;Daytime sleepiness;

Countries

China

Contacts

Public ContactYe Jin

The Third Affiliated Hospital Sun Yat-sen University

yejin@mail.sysu.edu.cn+86 20 85252690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026