dilated cardiomyopathy,ischemic cardiomyopathy
Conditions
Interventions
Observation group:None
Sponsors
Chuxiong Yi Autonomous Prefecture People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.The diagnosis of DCM and ICM was established according to the European Society of Cardiology (ESC) guidelines for heart failure, with left ventricular systolic dysfunction (left ventricular end-diastolic diameter = 50 mm and left ventricular ejection fraction < 50% on echocardiography). 2.DCM was defined as left ventricular systolic dysfunction in the absence of significant coronary artery disease (<50% stenosis), as confirmed by coronary angiography or coronary computed tomography angiography (CTA). 3.ICM was defined by the presence of significant coronary artery stenosis (=50%) or occlusion on coronary angiography or CTA. 4.Cohabiting relatives of patients with DCM were included as controls. Eligible controls were required to have no history of cardiovascular disease, with no evidence of structural or functional cardiac abnormalities on echocardiography, and no ischemic changes on electrocardiography.
Exclusion criteria
Exclusion criteria: 1. neurological or psychiatric disorders (including epilepsy, acute stroke, schizophrenia, anxiety or depression, and neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, or Huntington’s disease);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High-risk disease-causing gene;Selenoprotein P; | — |
Countries
China
Contacts
Public ContactLi Mei Zhang
Chuxiong Yi Autonomous Prefecture People's Hospital
Outcome results
None listed