Chronic Hepatitis B
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age greater than 18 years; 2.It complies with the relevant diagnostic criteria in the "Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2022 Edition)" formulated by the Hepatology Branch of the Chinese Medical Association and the Infectious Diseases Branch of the Chinese Medical Association; 3.All the patients were positive for HBsAg, positive or negative for HBeAg, and positive for HBV-DNA; 4.Take ETV or TAF for 48 weeks; 5.There are systematic examination results to determine the therapeutic effect of the drug;
Exclusion criteria
Exclusion criteria: 1.Patients with combined AIDS, viral hepatitis C, tuberculosis; 2.Pregnant or lactating women; 3.Combined HIV infection; 4.Previously received treatment with other anti-HBV infection drugs or immunomodulatory drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HBV-DNA negative conversion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| ALT negative conversion rate;HBeAg negative conversion rate; | — |
Countries
China
Contacts
Public ContactZiye Zhou
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed