Diarrhea
Conditions
Interventions
Queue 1 (Saccharomyces boulardii Powder):None
Sponsors
Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China
Eligibility
Sex/Gender
All
Age
No minimum to 14 Years
Inclusion criteria
Inclusion criteria: 1.Hospitalized pediatric patients aged 6 months to 14 years, regardless of sex; 2.Diagnosed with complicated appendicitis and underwent surgical treatment, with diarrhea developing within one week postoperatively; 3.No diarrhea symptoms upon hospital admission; 4.Informed consent signed by the legal guardian;
Exclusion criteria
Exclusion criteria: 1.Patients diagnosed prior to admission with infectious diarrhea (e.g., rotavirus infection), irritable bowel syndrome, or inflammatory bowel disease; 2.Patients with sepsis or severe infections; 3.Patients receiving immunosuppressants, other probiotic preparations, or antifungal agents; 4.Patients with central venous catheters (including CVC, PICC, or implantable ports) or admitted to the ICU during the treatment period; 5.Patients allergic to any component of this product, or those with fructose or lactose intolerance; 6.Pediatric patients concurrently taking other traditional Chinese medicines with diarrheal effects during the enrollment period; 7.Patients (or their parents/guardians) exhibiting poor compliance or non-cooperation with treatment, rendering efficacy assessment impossible; 8.Patients currently enrolled in other clinical trials;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 72-hour diarrhea treatment efficacy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of Diarrhea;Duration of Diarrhea;Adverse Event Incidence Rate;Number of bowel movements per day;Stool consistency; | — |
Countries
China
Contacts
Public ContactYan Huan
Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China
Outcome results
None listed