Lumbar disc herniation
Conditions
Interventions
Group C:Patients were given 2ug/kg dexmedetomidine hydrochloride nasal spray
Group A:Nasal spray of physiological saline solution
Group B:Patients were given 1ug/kg dexmedetomidine hydrochloride nasal spray
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. Patients who have failed conservative treatment and are scheduled to undergo intervertebral foramen endoscopy; 3. ASA?~?; 4. The patient is informed and signs their consent for this study.
Exclusion criteria
Exclusion criteria: 1. Patients not suitable for nasal spray administration or unwilling to accept nasal administration; 2. Individuals allergic to any medication used in this experiment; 3. Patients with systolic blood pressure 140 mmHg and diastolic blood pressure 90 mmHg; 4. Patients with heart rate (HR) 100 bpm; 5. Individuals with a history of allergic rhinitis, nasal surgery, and respiratory infections within the past 2 weeks; 6. Patients with severe cardiovascular and cerebrovascular abnormalities as well as liver and kidney dysfunction before surgery; 7. Patients who have been regularly taking other analgesics (such as opioids) recently; 8. Hearing impairment, language comprehension impairment, mental illness, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numerical Rating Scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Richmond Agitation-Sedation Scale rating;blood pressure;Pulse oxygen saturation;heart rate;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactLinlin Zhao
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed