Atherosclerosis
Conditions
Interventions
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients meeting all of the following criteria are eligible for inclusion: 1. Able to understand the purpose of the study, voluntarily participate in the research, and sign the informed consent form. 2. Aged 18 years or older, regardless of gender. 3. Have undergone cervical or lower extremity vascular ultrasound examination showing atherosclerotic lesions, but without significant stenosis (stenosis >=50%).
Exclusion criteria
Exclusion criteria: Patients will be excluded from participation if they present with any of the following conditions: 1. Patients with a confirmed diagnosis of ASCVD, including: coronary artery disease, hemorrhagic or ischemic stroke, peripheral atherosclerotic occlusive disease; 2. Uncontrolled hypertension, defined as SBP >=180 mmHg and/or DBP >=110 mmHg; 3. Uncontrolled arrhythmias: such as frequent atrial premature beats >30 beats/min, frequent ventricular premature beats >10 beats/min, etc.; 4. Moderate to severe aortic regurgitation, aortic aneurysm, aortic dissection; 5. Valvular heart disease, congenital heart disease, cardiomyopathy, and symptomatic congestive heart failure; 6. Lower extremity infection, phlebitis, varicose veins, deep vein thrombosis; 7. Concomitant malignant tumors or other diseases with poor prognosis; 8. Pregnant women; 9. Any other factors that the investigator deems unsuitable for inclusion in or completion of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulse wave velocity;CO2output,VCO2;Respiratory exchange rate, RER; RER=VCO2/VO2;Peakoxygen uptake,VO2peak;Anaerobic threshold,AT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vascular ultrasound examination;High-resolution magnetic resonance imaging of the carotid artery;Vascular endothelial function status;Oxygen uptake, VO2; | — |
Countries
China
Contacts
Public ContactZhao Wei
Peking University Third Hospital
Outcome results
None listed