Traumatic Optic Neuropathy
Conditions
Interventions
S3 Non-surgical Conservative Strategy Group: Decision not to undergo ETOCD:None
S2 Initial Steroid Strategy Group:None
S1 Early ETOCD Strategy Group:None
Sponsors
Beijing Childrens Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1.Pediatric age group: 0–18 years; 2. A definitive history of craniofacial trauma, with the initial specialist evaluation for TON conducted at our institution within =4 years, or poor/absent light pursuit and grasping reflexes in those =7 years; subjects aged >=16 years with full civil capacity may self-consent);
Exclusion criteria
Exclusion criteria: 1.Ruptured eyeball, optic nerve transection, or open craniocerebral injury requiring emergency craniotomy; 2.Concomitant severe intracranial hematoma (midline shift >5 mm) or signs of brain herniation; 3.Pre-existing underlying diseases affecting vision, such as optic nerve developmental abnormalities, glaucoma, or retinopathy; 4.Pre-injury ipsilateral amblyopia or blindness in the affected eye; 5.Severe concurrent ocular injuries that preclude differentiation of the source of vision loss (e.g., severe vitreous hemorrhage, retinal detachment, macular laceration, etc.), which may serve as an exclusion criterion or a preset condition for sensitivity analysis; 6.Inability to complete the 6-month follow-up (e.g., patients from other regions unwilling to return to the hospital and unable to provide local ophthalmological examination reports);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-Month Visual Improvement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Optical Coherence Tomography;Visual Evoked Potential improvement;Rate of Visual Improvement at 1 Week and 1 Month Postoperatively; | — |
Countries
China
Contacts
Public ContactNi Xin
Beijing Childrens Hospital,Capital Medical University
Outcome results
None listed