Tinnitus
Conditions
Interventions
Standard Treatment Control Group:Standard repetitive transcranial magnetic stimulation
Sham / Placebo Control Group:Placebo sham stimulation
Precision-Targeted rTMS Group:Personalized brain model-guided robotic arm navigated precision-targeted repetitive transcranial magnetic stimulation
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years and = 6 months; 3. Right-handed; 4. Capable of independently completing all scale assessments; 5. Previously unresponsive to drug treatment, and voluntarily participating in the study and signing the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Objective tinnitus (vascular, myogenic, or other types audible to others), or tinnitus caused by an identifiable active etiology, such as: acute otitis media, acute phase of Ménière's disease, acoustic neuroma, active temporomandibular joint disorder, etc.; 2.Contraindications to rTMS: including metal foreign bodies in the skull, cardiac pacemaker, wires or metal stents in the heart, traumatic brain injury, increased intracranial pressure, abnormal brain signs or intracranial tumors, cerebrovascular disease, neurodegenerative diseases of the cranial nerves, non-removable metal objects in or around the body, history of epilepsy or family history of epilepsy, history of electroconvulsive therapy, pregnancy; 3.Communication disorders or inability to cooperate; 4.Contraindications to MRI (e.g., presence of ferromagnetic aneurysm clips, pacemakers); 5.Use of sedatives or GABA-acting medications within the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| HAMD score;Beck Depression Inventory (BDI);HADS score; | — |
Countries
China
Contacts
Public ContactDuoduo Tao
The First Affiliated Hospital of Soochow University
Outcome results
None listed