Postoperative Sore Throat
Conditions
Interventions
Experimental group:Lubrication treatment of the tracheal tube: Use a 5 ml sterile medical syringe to withdraw 2.5 ml of Kami-gel, and apply it evenly on the surface of the cuff and on the part of the
Control group:Lubrication treatment of the tracheal tube: Use normal saline to evenly apply on the surface of the cuff, on the part of the tube 4 cm above the cuff, and on the tip of the laryngoscope.
Sponsors
Women and Children's Medical Center Affiliated to Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
8 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1.Age between 8 and 17 years, inclusive, regardless of gender 2.Pediatric patients scheduled for elective non-neck, non-laryngeal, and non-oropharyngeal surgery under general anesthesia with orotracheal intubation 3.American Society of Anesthesiologists (ASA) physical status class I-II 4.Anticipated duration of endotracheal tube placement >= 2 hours 5.Written informed consent obtained from the parent(s)/legal guardian(s) and assent from the child, when appropriate
Exclusion criteria
Exclusion criteria: 1.Children with oropharyngeal or cervical anatomical abnormalities 2.Children with a history of difficult airway surgery or anticipated difficult airway; 3.Children with upper respiratory tract infection within the past two weeks or any medical history accompanied by sore throat, hoarseness, cough, or sputum production; 4.Children with a history of airway hyperresponsiveness diseases (e.g., bronchial asthma, cough-variant asthma, chest tightness–variant asthma, etc.); 5.Children scheduled for neck, laryngeal, or oropharyngeal surgery; 6.Children requiring nasogastric or orogastric tube placement; 7.Children requiring postoperative mechanical ventilation; 8.Children with severe systemic diseases or conditions requiring long-term immunosuppressive therapy, such as: congenital or severe acquired cardiac disease, renal insufficiency (eGFR < 30 mL·min?¹·1.73 m?²), hepatic insufficiency (Child-Pugh class C or high MELD score), active hematologic malignancy, congenital or acquired immunodeficiency, and chronic diseases requiring long-term systemic immunosuppression/glucocorticoid therapy (e.g., systemic lupus erythematosus, rheumatoid arthritis, Crohn's disease, ulcerative colitis, severe allergic disorders, etc.); 9.Children undergoing thoracic surgery; 10.Children with intellectual disability, psychiatric disorders, or other conditions that may hinder compliance with follow-up assessments; 11.Children with known hypersensitivity to lidocaine or any components related to chamomile (Matricaria chamomilla); 12.Children who have participated in another clinical trial within 30 days prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Sore Throat; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative cough;Airway reaction after extubation;Postoperative hoarseness; | — |
Countries
China
Contacts
Public ContactSong Xingrong
Guangzhou Women and Children's Medical Center, Affiliated to Guangzhou Medical University
Outcome results
None listed