Post-stroke cognitive impairment
Conditions
Interventions
Control group:On the basis of conventional drug treatment, cognitive rehabilitation training and cerebellar rTMS sham stimulation treatment were received once a day, five times a week, for four consec
Intervention group:On the basis of conventional drug treatment, cognitive rehabilitation training and cerebellar rTMS treatment were received once a day, five times a week, for four consecutive weeks.
Sponsors
Second Affiliated Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years, both genders. 2. Diagnosed with stroke according to the diagnostic criteria established by the Fourth National Cerebrovascular Disease Academic Conference in 1995, confirmed by cranial CT or MRI. 3. Stroke duration >=6 months. 4. Presence of post-stroke cognitive impairment: MMSE score <=24 (for those with junior high school education or above), <=20 (for those with primary school education), or <=17 (for illiterate individuals). 5. Patients are conscious, with stable vital signs, and able to cooperate with the assessments. 6. No psychiatric disorders, severe aphasia, or hearing comprehension impairment. 7. The patient or their legally authorized representative agrees to participate in this study and signs the written informed consent document.
Exclusion criteria
Exclusion criteria: 1.Cognitive impairment caused by other neurological diseases, such as Alzheimer's disease, Parkinson's disease, and hydrocephalus; 2. Accompanied by severe mental, intellectual disabilities or visual and auditory impairments, unable to cooperate to complete various functional evaluations; 3.Within three months after cognitive impairment, there was drug/alcohol abuse/dependence; 4.Contraindications for rTMS treatment, such as epilepsy patients, pregnant or lactating women, or the use of metal or electronic implant devices (such as deep brain stimulators, ventriculoperitoneal shunt devices, aneurysm clips, pacemakers, cochlear implants, scalp surgical nails).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse events; | — |
Countries
China
Contacts
Public ContactLi Fenge
Second Affiliated Hospital of Shantou University Medical College
Outcome results
None listed