Lung cancer
Conditions
Interventions
Group of severe radiation-induced lung injury:None
Group of non-severe radiation-induced lung injury:None
Sponsors
Huzhou Center Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inoperable locally advanced non-small cell lung cancer (NSCLC) confirmed by histopathological examination was treated at Huzhou Central Hospital with volumetric modulated arc therapy (VMAT). The total radiation dose was >= 50 Gy, with a fractionated dose of 1.8 - 2.5 Gy per session, and the clinical and radiation treatment data were complete.
Exclusion criteria
Exclusion criteria: 1. Concurrent primary malignancies; 2. History of splenectomy, active autoimmune disease, or long-term use of immunosuppressive agents; 3. Receipt of >=3 days of prolonged corticosteroid therapy (beyond physiologic replacement doses) during radiotherapy; 4. Missing critical follow-up data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severe lymphocyte depletion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival, OS;Progression Free Survival, PFS; | — |
Countries
China
Contacts
Public Contactshuheng shang
Huzhou Center Hospital
Outcome results
None listed