Ultrasound soft maker in the first trimester
Conditions
Interventions
Gold Standard:Genetic test results, pregnancy outcomes, and follow-up ultrasound
Index test:ultrasound soft maker in the first trimester
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.early pregnancy; 2.Normal cases of fixed motion ultrasound images stored in standard scanning facets of individual anatomical structures are obtained according to guidelines established by the International Society of Ultrasound in Obstetrics and Gynecology; 3.The prenatal ultrasound imaging is complete; 4.Follow-up data were complete, including pregnancy outcomes, chromosomal findings, or echo ultrasound findings; 5.The subject himself agrees to participate in this clinical study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Screening at 11+6-13+6 weeks of gestation suggests cases of fetal developmental abnormalities, and cases of incomplete follow-up examination and unclear pregnancy outcome; 2.Screening at 11+6-13+6 weeks gestation suggests fetal death with unknown cause;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ultrasound soft maker in the first trimester; | — |
Secondary
| Measure | Time frame |
|---|---|
| specificity;sensitivity;positive likelihood ratio (LR+);Youden's index;negative likelihood ratio (LR-);negative predictive value (NPV);positive predictive value (PPV); | — |
Countries
China
Contacts
Public ContactDi Na
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed