Dengue fever, Chikungunya fever
Conditions
Interventions
chikungunya:None
Dengue:None
health control:None
Sponsors
The People's Hospital of Baiyun District Guangzhou
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Voluntary signing of an informed consent form; 2. Aged between 25 and 65 years, regardless of gender; 3. Participants diagnosed with dengue fever or chikungunya fever based on a comprehensive assessment of their epidemiological evidence, clinical presentation and laboratory test results; a matched group of healthy individuals with no fever and no history of viral exposure will be enrolled at the same time.
Exclusion criteria
Exclusion criteria: 1. Use of antibiotics, antifungals or probiotics within 3 months prior to enrolment; 2. Chronic gastrointestinal disorders (such as inflammatory bowel disease, irritable bowel syndrome, chronic diarrhoea or constipation); 3. Concurrent acute infections (such as bacterial dysentery or COVID-19), or confirmed complications (such as dengue shock syndrome or neuropathy caused by chikungunya fever); 4. Patients in specific physiological conditions (pregnant or breastfeeding women, or patients who have undergone gastrointestinal surgery within the past 3 months).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of feces and skin microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Record clinical symptoms including peak temperature, time to defervescence, length of hospital stay, time for rash resolution, and incidence of clinical symptoms (headache, arthralgia, myalgia, fever,;Routine admission blood tests (complete blood count, hypersensitive C-reactive protein, erythrocyte sedimentation rate, cytokines, coagulation, liver function, kidney function, etc.); | — |
Countries
China
Contacts
Public ContactYaqiu Long
The People's Hospital of Baiyun District Guangzhou
Outcome results
None listed