Knee joint disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 20 to 80; 2. With an overall physical condition of I or II as assessed by the American Society of Anesthesiologists (ASA) score; 3. Clearly diagnosed with knee osteoarthritis before the operation, with symptoms mainly on one side and ineffective after conservative treatment; 4. Patients planning to undergo unilateral total knee arthroplasty (TKA) (including those who have undergone contralateral knee replacement); 5. Those who are not allergic to the drugs in this study; 6. Those willing to provide a written informed consent and participate and comply with the study.
Exclusion criteria
Exclusion criteria: 1. Patients undergoing bilateral total knee arthroplasty (TKA), unicompartmental knee joint replacement, or revision surgery; 2. Patients with severe joint lesions in both knees simultaneously; 3. Patients with severe underlying diseases and poorly controlled conditions; 4. Patients with a history of stroke or neurological or mental disorders (severe mental disorders, psychological problems, and inability to communicate); 5. Patients with a history of drug addiction, drug use, past dependence on anesthetic drugs, drug abuse history, and those currently receiving hormone therapy; 6. Patients allergic to the drugs in this study; 7. Patients with central and peripheral nervous system problems that prevent them from completing the postoperative rehabilitation plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| ROM of Knee;KOOC score;SF-12 Score;Concomitant medication; | — |
Countries
China
Contacts
Shanghai 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine